WHO, FN, CDC mfl. har noget at fortælle om verdens mest succesfulde en-cellede organisme

For the record. Uddrag af Internationale advarsler, opråb og opfordringer vedr. Toxoplasma;

 
Unit for Gastrointestinal Infections, Robert Koch Institute Germany (2016): "High numbers of seroconversions during pregnancies pose substantial risks for unborn children. Efforts to raise awareness of toxoplasmosis in public health programs targeting to T. gondii transmission control are therefore strongly advocated."

Flegr et al. (2016) "Results of the present cohort study, along with the previous data from many case-control studies or ecological studies suggest that latent toxoplasmosis represents a large and so far underrated public health problem."

WHO Europe (2016) "Toxoplasmosis: greater awareness needed (..) More awareness is needed in Europe about the risk factors for infection of Toxoplasma gondii, according to the World Health Organization (WHO)."

Statens Serum Institut (2016): "Langt de fleste infektioner forløber formentlig uden symptomer, men da infektionen er livslang, kan immunsuppression lede til reaktivering af infektionen med dissemineret sygdom til følge." (Bemærk: som vist nedenfor leder Tg infektionen i sig selv til immunsuppression)

Kugler et al. (2016) "Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes" (.. ) leads to an immunocompromised state that both promotes chronic toxoplasma infection and leads to decreased resistance to challenge with an unrelated pathogen." 

WHO (2015): "The disease burden due to most foodborne parasites is highly focal and results in significant morbidity and mortality among vulnerable populations."

Sinai et al. (2015): ”Led by Anthony Sinai, professor at the UK College of Medicine, the study has significant implications on the understanding of chronic toxoplasmosis in the brain, a condition suggested to contribute to a range of neurological diseases including schizophrenia in humans” “These findings directly challenge the prevailing notion of bradyzoites as dormant nonreplicative entities in chronic toxoplasmosis and have implications on our understanding of this enigmatic and clinically important life cycle stage. This fundamentally alters our understanding of chronic toxoplasmosis,” 

Flegr et al. (2014) "Toxoplasmosis – A Global Threat. Correlation of Latent Toxoplasmosis with Specific Disease Burden.."

Center for Disease Control, CDC, USA (2014): "Parasitic infections affect millions around the world causing seizures,blindness, infertility, heart failure, and even death (..) While parasitic infections can sometimes affect millions of people, they often cause few symptoms and go unnoticed (..) More than 60 million people (in US) are chronically infected with Toxoplasma gondii (..) The CDC experts noted that most parasitic infections can be prevented and many are treatable. But they most often go undiagnosed and untreated because people don't know they are at risk or infected, and many doctors, unfamiliar with these infections, fail to diagnose or treat them properly

United Nations/FAO (2014): “Despite their huge social costs and global impactsinformation is generally lacking regarding just where these parasites come from, how they live in the human body, and – most importantly – how they make people sick (..) But considering the problems they cause, these parasites do not get the attention they deserve. We hope that by releasing a top 10 ranking we can increase awareness among policy makers, the media and the general public about this major public health issue.


Prime Minister of Iceland (2014): "PM Fears Behavior-Changing Microbe in Imported Meat"

Gary Smith et al. (2014), Up to 1/5 of all schizophrenia related to Tg: "By finding out how important a factor T. gondii infection is, this work might inform our attitude to researching the subject.Instead of ridiculing the idea of a connection between T. gondii and schizophrenia because it seems so extraordinary, we can sit down and consider the evidence. Perhaps then we might be persuaded to look for more ways to reduce the number of people infected with toxoplasma."

Flegr et al (2014) The existence of a strong correlation between the prevalence of toxoplasmosis and health of population (..) suggests that 'asymptomatic' latent toxoplasmosis could have a large impact on public health.

WHO (2013): "Our estimates of the incidence and burden of CT point to a very large global burden of toxoplasmosis. The burden is even greater when various conditions and problems related to toxoplasmosis are considered. For example, toxoplasmosis is known to cause chorioretinitis in healthy adults and especially in people who have immunosuppression. (..) There are also increasing reports of neurological, psychiatric or psychomotor disorders related to “latent” toxoplasmosis, and of a higher frequency of road traffic accidents among seropositive individuals. Even if toxoplasmosis accounts for only a small fraction of these problems in the population, the global burden of disease attributable to toxoplasmosis is considerably greater than suggested by our CT data. In addition, since much toxoplasmosis can be prevented, at least in theory, by observing appropriate food hygiene, the disease deserves a higher profile in GDB studies and should not be subsumed into other disease categories, such as “congenital disorders”.

Professor Jaroslav Flegr: (2012) “'When you add up all the different ways it can harm us,' says Flegr, 'Toxoplasma might even kill as many people as malaria, or at least a million people a year.'” “There is strong psychological resistance to the possibility that human behavior can be influenced by some stupid parasite,

Furtado et al. (2011) "Toxoplasmosis; A Global Threat"

Wiki (2009): Overall, Toxoplasmosis can have extremely detrimental effects on anyone who contracts the disease. Although most immunocompetent patients are able to combat the parasite, many individuals who are either suffering from a disease that renders them immunocompromised, pregnant women, or individuals whose medication weakens their immunity might find that Toxoplasmosis has more of a negative impact on their bodies than expected. Thus, it is very important to practice prevention of the disease, so that treatment does not need to be employed.

0 Kommentarer

Log ind for at kommentere